Congenital craniopharyngioma diagnosed at 18 week gestation

Mennat Allah M. Ewais, Marissa V. Ylagan, Andrea R. Gilbert

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Brain tumors arising in the perinatal period are exceedingly rare and, of these, craniopharyngiomas comprise a small proportion. We report a case of craniopharyngioma diagnosed by prenatal ultrasound and confirmed by autopsy with histopathologic examination in a newborn delivered at 25 weeks 4 days gestation, which, to our knowledge, is the earliest diagnosed case of craniopharyngioma at 18 week gestation published in the English literature to date. Prenatal ultrasound imaging of a macrocephalic fetus detected a large irregular echogenic mass consistent with brain tumor at 18 weeks gestation. Gross autopsy evaluation following delivery at 25 weeks and 4 days revealed a solid and cystic mass that encompassed the entirety of the intracranial space without any grossly recognizable brain tissue. Histologic examination confirmed the diagnosis of adamantinomatous craniopharyngioma.

Idioma originalEnglish (US)
Número de artículo300576
PublicaciónHuman Pathology Reports
EstadoPublished - nov 2021

ASJC Scopus subject areas

  • Pathology and Forensic Medicine


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