Gas chromatography-mass spectrometry was used to identify a dopamine metabolite isolated from the substantia nigra of parkinsonian brain tissue. Incubation of dopamine with monoamine oxidase B gave the same product which was identified as 3,4-dihydroxyphenylacetaldehyde. The structure of the compound was established by chemical synthesis, metastable ion measurement and high-resolution mass spectrometry.
|Idioma original||English (US)|
|Número de páginas||8|
|Publicación||Journal of Chromatography B: Biomedical Sciences and Applications|
|Estado||Published - may. 5 1993|
|Publicado de forma externa||Sí|
ASJC Scopus subject areas