Colony-stimulating factor-1 exerts direct effects on the proliferation and invasiveness of endometrial epithelial cells

Sabitha Aligeti, Nameer B. Kirma, Peter A. Binkley, Robert S. Schenken, Rajeshwar Rao Tekmal

Producción científica: Articlerevisión exhaustiva

14 Citas (Scopus)

Resumen

Although macrophage colony-stimulating factor (CSF-1) has been suggested to play a role in maintaining the chronic inflammatory response in endometriosis, our data suggest that CSF-1 may also play a role in early endometriosis lesion formation. We have shown that CSF-1, in an autocrine fashion, has a direct effect on endometrial epithelial cell proliferation and attachment to peritoneal mesothelial cells, early steps in endometriosis lesion formation on the peritoneum.

Idioma originalEnglish (US)
Páginas (desde-hasta)2464-2466
Número de páginas3
PublicaciónFertility and sterility
Volumen95
N.º8
DOI
EstadoPublished - jun 30 2011

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Reproductive Medicine

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