Clinical feasibility study of combined optoacoustic and ultrasonic imaging modality providing coregistered functional and anatomical maps of breast tumors

Jason Zalev, Don Herzog, Bryan Clingman, Tom Miller, Kenneth Kist, N. Carol Dornbluth, Barbara M Mccorvey, Pamela Otto, Sergey Ermilov, Vyacheslav Nadvoretsky, Andre Conjusteau, Richard Su, Dmitri Tsyboulski, Alexander Oraevsky

Producción científica: Conference contribution

14 Citas (Scopus)

Resumen

Two-dimensional optoacoustic imaging with a hand-held probe operated in backward mode is being developed for diagnostic imaging of breast cancer to evaluate the feasibility of a dual-modality optoacoustic plus ultrasonic system that maps functional information of anatomical tissue structures with ultrasonic resolution. Tissue is illuminated at 757nm and 1064nm for optical contrast between hypoxic blood of breast carcinomas and normally oxygenated blood in benign masses. The system is optimized and calibrated in phantoms for a pilot clinical study of patients with breast masses suspected for malignancy. Capability of the non-invasive system to improve detection and diagnosis of breast tumors is discussed.

Idioma originalEnglish (US)
Título de la publicación alojadaPhotons Plus Ultrasound
Subtítulo de la publicación alojadaImaging and Sensing 2012
DOI
EstadoPublished - 2012
EventoPhotons Plus Ultrasound: Imaging and Sensing 2012 - San Francisco, CA, United States
Duración: ene 22 2012ene 24 2012

Serie de la publicación

NombreProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volumen8223
ISSN (versión impresa)1605-7422

Other

OtherPhotons Plus Ultrasound: Imaging and Sensing 2012
País/TerritorioUnited States
CiudadSan Francisco, CA
Período1/22/121/24/12

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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