@inproceedings{4fa0237ad2ee4666a3d0c38e081a6b2d,
title = "Clinical feasibility study of combined opto-acoustic and ultrasonic imaging modality providing coregistered functional and anatomical maps of breast tumors",
abstract = "We report on findings from the clinical feasibility study of the Imagio{\texttrademark}. Breast Imaging System, which acquires two-dimensional opto-acoustic (OA) images co-registered with conventional ultrasound using a specialized duplex hand-held probe. Dual-wavelength opto-acoustic technology is used to generate parametric maps based upon total hemoglobin and its oxygen saturation in breast tissues. This may provide functional diagnostic information pertaining to tumor metabolism and microvasculature, which is complementary to morphological information obtained with conventional gray-scale ultrasound. We present co-registered opto-acoustic and ultrasonic images of malignant and benign tumors from a recent clinical feasibility study. The clinical results illustrate that the technology may have the capability to improve the efficacy of breast tumor diagnosis. In doing so, it may have the potential to reduce biopsies and to characterize cancers that were not seen well with conventional gray-scale ultrasound alone.",
author = "Jason Zalev and Bryan Clingman and Smith, {Remie J.} and Don Herzog and Tom Miller and Stavros, {Anthony T} and Sergey Ermilov and Andre Conjusteau and Dmitri Tsyboulski and Oraevsky, {Alexander A.} and Kenneth Kist and Dornbluth, {N. C.} and Pamela Otto",
year = "2013",
month = may,
day = "28",
doi = "10.1117/12.2009112",
language = "English (US)",
isbn = "9780819493507",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Photons Plus Ultrasound",
note = "Photons Plus Ultrasound: Imaging and Sensing 2013 ; Conference date: 03-02-2013 Through 05-02-2013",
}