Clinical feasibility study of combined opto-acoustic and ultrasonic imaging modality providing coregistered functional and anatomical maps of breast tumors

Jason Zalev, Bryan Clingman, Remie J. Smith, Don Herzog, Tom Miller, Anthony T Stavros, Sergey Ermilov, Andre Conjusteau, Dmitri Tsyboulski, Alexander A. Oraevsky, Kenneth Kist, N. C. Dornbluth, Pamela Otto

Producción científica: Conference contribution

12 Citas (Scopus)

Resumen

We report on findings from the clinical feasibility study of the Imagio™. Breast Imaging System, which acquires two-dimensional opto-acoustic (OA) images co-registered with conventional ultrasound using a specialized duplex hand-held probe. Dual-wavelength opto-acoustic technology is used to generate parametric maps based upon total hemoglobin and its oxygen saturation in breast tissues. This may provide functional diagnostic information pertaining to tumor metabolism and microvasculature, which is complementary to morphological information obtained with conventional gray-scale ultrasound. We present co-registered opto-acoustic and ultrasonic images of malignant and benign tumors from a recent clinical feasibility study. The clinical results illustrate that the technology may have the capability to improve the efficacy of breast tumor diagnosis. In doing so, it may have the potential to reduce biopsies and to characterize cancers that were not seen well with conventional gray-scale ultrasound alone.

Idioma originalEnglish (US)
Título de la publicación alojadaPhotons Plus Ultrasound
Subtítulo de la publicación alojadaImaging and Sensing 2013
DOI
EstadoPublished - 2013
EventoPhotons Plus Ultrasound: Imaging and Sensing 2013 - San Francisco, CA, United States
Duración: feb 3 2013feb 5 2013

Serie de la publicación

NombreProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volumen8581
ISSN (versión impresa)1605-7422

Other

OtherPhotons Plus Ultrasound: Imaging and Sensing 2013
País/TerritorioUnited States
CiudadSan Francisco, CA
Período2/3/132/5/13

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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