Resumen
Context: Chromogranin A (CgA) is a novel biomarker with potential to assess mortality risk of patients with severe sepsis.Objective: Assess association of CgA levels and mortality risk of severely septic patients.Methods: Serum CgA levels were measured in 50 hospitalized, severely septic patients with organ failure <48 h.Results: Higher CgA levels trended toward higher ICU and hospital mortality. Patients without cardiovascular disease who died in the ICU had higher median (IQR) CgA levels 602.3 (343.3, 1134.3) ng/ml versus 205.5 (130.7, 325.9) ng/ml, p = 0.01.Conclusions: High CgA levels predict ICU mortality in severely septic patients without prior cardiovascular disease.
Idioma original | English (US) |
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Páginas (desde-hasta) | 171-176 |
Número de páginas | 6 |
Publicación | Biomarkers |
Volumen | 20 |
N.º | 3 |
DOI | |
Estado | Published - abr 3 2015 |
ASJC Scopus subject areas
- Biochemistry
- Clinical Biochemistry
- Health, Toxicology and Mutagenesis