Cardiovascular Complications in Coronavirus Disease 2019-Pathogenesis and Management

Marcos I. Restrepo, Judith Marin-Corral, Juan J. Rodriguez, Valeria Restrepo, Rodrigo Cavallazzi

Producción científica: Review articlerevisión exhaustiva

3 Citas (Scopus)

Resumen

The coronavirus disease 2019 (COVID-19) pandemic has caused a devastating impact on morbidity and mortality around the world. Severe acute respiratory syndrome-coronavirus-2 has a characteristic tropism for the cardiovascular system by entering the host cells and binding to angiotensin-converting enzyme 2 receptors, which are expressed in different cells, particularly endothelial cells. This endothelial injury is linked by a direct intracellular viral invasion leading to inflammation, microthrombosis, and angiogenesis. COVID-19 has been associated with acute myocarditis, cardiac arrhythmias, new onset or worsening heart failure, ischemic heart disease, stroke, and thromboembolic disease. This review summarizes key relevant literature regarding the epidemiology, diagnosis, treatment, and preventive measures related to cardiovascular complications in the setting of COVID-19.

Idioma originalEnglish (US)
Páginas (desde-hasta)21-34
Número de páginas14
PublicaciónSeminars in Respiratory and Critical Care Medicine
Volumen44
N.º1
DOI
EstadoPublished - feb 2023

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Pulmonary and Respiratory Medicine

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