@article{fbc51841f7ec457e80501ef9142e6f82,
title = "Breakthrough invasive fungal infections: Who is at risk?",
abstract = "The epidemiology of invasive fungal infections (IFIs) in immunocompromised individuals has changed over the last few decades, partially due to the increased use of antifungal agents to prevent IFIs. Although this strategy has resulted in an overall reduction in IFIs, a subset of patients develop breakthrough IFIs with substantial morbidity and mortality in this population. Here, we review the most significant risk factors for breakthrough IFIs in haematology patients, solid organ transplant recipients, and patients in the intensive care unit, focusing particularly on host factors, and highlight areas that require future investigation.",
keywords = "breakthrough fungal infections, fungal infections, risk factors",
author = "Jenks, {Jeffrey D.} and Cornely, {Oliver A.} and Chen, {Sharon C.A.} and Thompson, {George R.} and Martin Hoenigl",
note = "Funding Information: This work was supported using funds from the Oesterreichische Nationalbank (Anniversary Fund, project number 15346) and has been partially supported by grants from the National Institutes of Health (MH 113477, AI106039, AI036214 and MH062512). The funders had no role in the study design, data collection, analysis, interpretation and decision to publish, in the writing of the manuscript, or in the decision to submit the manuscript for publication. Publisher Copyright: {\textcopyright} 2020 Wiley-VCH GmbH",
year = "2020",
month = oct,
day = "1",
doi = "10.1111/myc.13148",
language = "English (US)",
volume = "63",
pages = "1021--1032",
journal = "Mykosen",
issn = "0933-7407",
publisher = "Wiley-Blackwell",
number = "10",
}