Biomarkers: Population Screening and Risk-Stratification

I. Ratjen, R. S. Vasan, W. Lieb

Producción científica: Chapter


Biomarkers are increasingly considered as instruments for population screening and cardiovascular risk stratification. In addition to meeting key requirements that apply to all biomarkers, screening biomarkers should be able to identify—in a large sample screened—those individuals who are currently free of cardiovascular disease (CVD) but who are at high risk of developing CVD in the future. Ideally, screening biomarkers capture the disease process at an early stage, for example, by detecting subclinical changes that predispose to clinically overt CVD. In order to improve risk stratification beyond established risk factors, novel biomarkers should improve the estimation of absolute disease risks and the reclassification of individuals in more appropriate risk categories.

Idioma originalEnglish (US)
Título de la publicación alojadaEncyclopedia of Cardiovascular Research and Medicine
Número de páginas11
ISBN (versión digital)9780128051542
ISBN (versión impresa)9780128096574
EstadoPublished - ene 1 2017
Publicado de forma externa

ASJC Scopus subject areas

  • General Medicine


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