Biomarkers for bipolar disorder: current status and challenges ahead

Antonio L. Teixeira, Gabriela D. Colpo, Gabriel R. Fries, Isabelle E. Bauer, Sudhakar Selvaraj

Producción científica: Review articlerevisión exhaustiva

53 Citas (Scopus)

Resumen

Introduction: Bipolar disorder (BD) is a chronic psychiatric disorder marked by clinical and pathophysiological heterogeneity. There is a high expectation that personalized approaches can improve the management of patients with BD. For that, identification and validation of potential biomarkers are fundamental. Areas covered: This manuscript will critically review the current status of different biomarkers for BD, including peripheral, genetic, neuroimaging, and neurophysiological candidates, discussing the challenges to move the field forward. Expert commentary: There are no lab or complementary tests currently recommended for the diagnosis or management of patients with BD. Panels composed by multiple biomarkers will probably contribute to stratifying patients according to their clinical stage, therapeutic response, and prognosis.

Idioma originalEnglish (US)
Páginas (desde-hasta)67-81
Número de páginas15
PublicaciónExpert Review of Neurotherapeutics
Volumen19
N.º1
DOI
EstadoPublished - ene 2 2019
Publicado de forma externa

ASJC Scopus subject areas

  • General Neuroscience
  • Clinical Neurology
  • Pharmacology (medical)

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