Biogenic amine metabolites in cerebrospinal fluid of depressed and manic patients

J. Mendels; A. Frazer; R. G. Fitzgerald; T. A. Ramsey; J. W. Stokes

doi:10.1126/science.175.4028.1380

Biogenic amine metabolites in cerebrospinal fluid of depressed and manic patients

J. Mendels
, A. Frazer
, R. G. Fitzgerald
, T. A. Ramsey
, J. W. Stokes

Producción científica: Article › revisión exhaustiva

116 Citas (Scopus)

Resumen

A reduction in 5-hydroxyindoleacetic acid in cerebrospinal fluid was found in depressed and manic patients both while they were symptomatic and also after treatment. The concentration of homovanillic acid was initially reduced and then tended to increase after treatment.

Idioma original	English (US)
Páginas (desde-hasta)	1380-1382
Número de páginas	3
Publicación	Science
Volumen	175
N.º	4028
DOI	https://doi.org/10.1126/science.175.4028.1380
Estado	Published - 1972
Publicado de forma externa	Sí

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title = "Biogenic amine metabolites in cerebrospinal fluid of depressed and manic patients",

abstract = "A reduction in 5-hydroxyindoleacetic acid in cerebrospinal fluid was found in depressed and manic patients both while they were symptomatic and also after treatment. The concentration of homovanillic acid was initially reduced and then tended to increase after treatment.",

author = "J. Mendels and A. Frazer and Fitzgerald, \{R. G.\} and Ramsey, \{T. A.\} and Stokes, \{J. W.\}",

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doi = "10.1126/science.175.4028.1380",

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T1 - Biogenic amine metabolites in cerebrospinal fluid of depressed and manic patients

AU - Mendels, J.

AU - Frazer, A.

AU - Fitzgerald, R. G.

AU - Ramsey, T. A.

AU - Stokes, J. W.

PY - 1972

Y1 - 1972

N2 - A reduction in 5-hydroxyindoleacetic acid in cerebrospinal fluid was found in depressed and manic patients both while they were symptomatic and also after treatment. The concentration of homovanillic acid was initially reduced and then tended to increase after treatment.

AB - A reduction in 5-hydroxyindoleacetic acid in cerebrospinal fluid was found in depressed and manic patients both while they were symptomatic and also after treatment. The concentration of homovanillic acid was initially reduced and then tended to increase after treatment.

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UR - https://www.scopus.com/pages/publications/0015521655#tab=citedBy

U2 - 10.1126/science.175.4028.1380

DO - 10.1126/science.175.4028.1380

M3 - Article

C2 - 5059569

AN - SCOPUS:0015521655

SN - 0036-8075

VL - 175

SP - 1380

EP - 1382

JO - Science

JF - Science

IS - 4028

ER -

Biogenic amine metabolites in cerebrospinal fluid of depressed and manic patients

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