Biochemical Determinants of Responsiveness to 5-Fluorouracil and Its Derivatives in Xenografts of Human Colorectal Adenocarcinomas in Mice

Pharmacology, Toxicology and Pharmaceutical Science

• Neoplasm 100%
• Tritium 66%
• Fluorouracil 50%
• Synthetase 50%
• Thymidine Phosphate 50%
• Colorectal Carcinoma 33%
• Floxuridine 33%
• Mouse 33%
• Pyrimidine 33%
• Enzyme 16%
• Pyroxylin 16%
• Protein 16%
• Thymidylate Synthase 16%
• Binding Potential 16%
• Enzyme Inhibition 16%
• Methylenetetrahydrofolic Acid 16%
• Fluorouridine 16%

Chemistry

• Thymidine 50%
• Concentration 50%
• Cofactor 33%
• Pyrimidine 33%
• 5-Fluorouracil 33%
• Biochemical 16%
• Protein 16%
• Enzyme Activity 16%
• Phosphate 16%
• Nitrocellulose 16%
• Membrane Filtration 16%
• 5-Fluorouridine 16%
• Potential 16%
• Time 16%
• EC 16%