@article{d0fad05adfce4a20b2ec5e4b5a50c7cd,
title = "Binding of FANCI-FANCD2 Complex to RNA and R-Loops Stimulates Robust FANCD2 Monoubiquitination",
abstract = "Fanconi anemia pathway has a well-known role in the repair of DNA crosslinks, but its recently identified role in suppression of co-transcriptional R-loops remains elusive. Here, Liang et al. show that FANCI-FANCD2 has intrinsic RNA and R-loop binding activity and provide mechanistic insights into FA pathway activation upon transcription stress.",
keywords = "DNA damage, FANCD2, FANCI-FANCD2, Fanconi anemia, R-loop, RNA, monoubiquitination, transcription perturbation",
author = "Zhuobin Liang and Fengshan Liang and Yaqun Teng and Xiaoyong Chen and Jingchun Liu and Simonne Longerich and Timsi Rao and Green, \{Allison M.\} and Collins, \{Natalie B.\} and Yong Xiong and Li Lan and Patrick Sung and Kupfer, \{Gary M.\}",
note = "Publisher Copyright: {\textcopyright} 2018 The Authors",
year = "2019",
month = jan,
day = "15",
doi = "10.1016/j.celrep.2018.12.084",
language = "English (US)",
volume = "26",
pages = "564--572.e5",
journal = "Cell Reports",
issn = "2211-1247",
publisher = "Cell Press",
number = "3",
}