Baboon as a nonhuman primate model for vaccine studies

Krishna K. Murthy; Mary T. Salas; Kenneth D. Carey; Jean L. Patterson

doi:10.1016/j.vaccine.2005.08.047

Baboon as a nonhuman primate model for vaccine studies

Krishna K. Murthy, Mary T. Salas, Kenneth D. Carey, Jean L. Patterson

Resultado de la investigación: Article › revisión exhaustiva

21 Citas (Scopus)

Resumen

Nonhuman primates are suitable and valid models to determine the safety, immunogenicity and efficacy of candidate vaccines that are being developed for human application. Among the nonhuman primates, baboons have been found to be ideal for vaccine studies because they are phylogenetically closer to humans, have a similar immune system and response and are available in large numbers. During the last two decades, numerous candidate vaccines have been evaluated in the baboon model.

Idioma original	English (US)
Páginas (desde-hasta)	4622-4624
Número de páginas	3
Publicación	Vaccine
Volumen	24
N.º	21
DOI	https://doi.org/10.1016/j.vaccine.2005.08.047
Estado	Published - may 22 2006

ASJC Scopus subject areas

Molecular Medicine
Immunology and Microbiology(all)
veterinary(all)
Public Health, Environmental and Occupational Health
Infectious Diseases

Acceder al documento

10.1016/j.vaccine.2005.08.047

Otros archivos y enlaces

Citar esto

@article{06d59caf480841f19b3ffc1f887526a4,

title = "Baboon as a nonhuman primate model for vaccine studies",

abstract = "Nonhuman primates are suitable and valid models to determine the safety, immunogenicity and efficacy of candidate vaccines that are being developed for human application. Among the nonhuman primates, baboons have been found to be ideal for vaccine studies because they are phylogenetically closer to humans, have a similar immune system and response and are available in large numbers. During the last two decades, numerous candidate vaccines have been evaluated in the baboon model.",

keywords = "Baboons, Candidate vaccines, Immunogenicity, Nonhuman primates",

author = "Murthy, {Krishna K.} and Salas, {Mary T.} and Carey, {Kenneth D.} and Patterson, {Jean L.}",

year = "2006",

month = may,

day = "22",

doi = "10.1016/j.vaccine.2005.08.047",

language = "English (US)",

volume = "24",

pages = "4622--4624",

journal = "Vaccine",

issn = "0264-410X",

publisher = "Elsevier BV",

number = "21",

}

TY - JOUR

T1 - Baboon as a nonhuman primate model for vaccine studies

AU - Murthy, Krishna K.

AU - Salas, Mary T.

AU - Carey, Kenneth D.

AU - Patterson, Jean L.

PY - 2006/5/22

Y1 - 2006/5/22

N2 - Nonhuman primates are suitable and valid models to determine the safety, immunogenicity and efficacy of candidate vaccines that are being developed for human application. Among the nonhuman primates, baboons have been found to be ideal for vaccine studies because they are phylogenetically closer to humans, have a similar immune system and response and are available in large numbers. During the last two decades, numerous candidate vaccines have been evaluated in the baboon model.

AB - Nonhuman primates are suitable and valid models to determine the safety, immunogenicity and efficacy of candidate vaccines that are being developed for human application. Among the nonhuman primates, baboons have been found to be ideal for vaccine studies because they are phylogenetically closer to humans, have a similar immune system and response and are available in large numbers. During the last two decades, numerous candidate vaccines have been evaluated in the baboon model.

KW - Baboons

KW - Candidate vaccines

KW - Immunogenicity

KW - Nonhuman primates

UR - http://www.scopus.com/inward/record.url?scp=33646839288&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33646839288&partnerID=8YFLogxK

U2 - 10.1016/j.vaccine.2005.08.047

DO - 10.1016/j.vaccine.2005.08.047

M3 - Article

C2 - 16198028

AN - SCOPUS:33646839288

SN - 0264-410X

VL - 24

SP - 4622

EP - 4624

JO - Vaccine

JF - Vaccine

IS - 21

ER -

Baboon as a nonhuman primate model for vaccine studies

Resumen

ASJC Scopus subject areas

Acceder al documento

Otros archivos y enlaces

Huella

Citar esto