George R. Thompson, Thomas F. Patterson

Producción científica: Chapter


The treatment of invasive aspergillosis remains difficult and until recently only polyenes and itraconazole were viable treatment options. However the development of newer triazoles (voriconazole, posaconazole) has been a welcome addition to the antifungal armamentarium. The proven efficacy of prophylactic posaconazole in high-risk patients, and the use of voriconazole during treatment of invasive aspergillosis have largely replaced amphotericin B and itraconazole use for these indications. Other extended-spectrum triazoles in preclinical development (ravuconazole, isavuconazole, and albaconazole) offer additional pharmacodynamic/pharmacokinetic advantages and will also be reviewed.

Idioma originalEnglish (US)
Título de la publicación alojadaAspergillosis
Subtítulo de la publicación alojadaFrom Diagnosis to Prevention
EditorialSpringer Netherlands
Número de páginas32
ISBN (versión digital)9789048124084
ISBN (versión impresa)9789048124077
EstadoPublished - 2010

ASJC Scopus subject areas

  • General Medicine


Profundice en los temas de investigación de 'Azoles'. En conjunto forman una huella única.

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