Autoimmune thyroid diseases in children

Prasanthi Pasala, Gary L. Francis

Resultado de la investigación: Review articlerevisión exhaustiva

11 Citas (Scopus)


Introduction: Autoimmune thyroid diseases (AIT) are common in children and may present with a variety of signs and symptoms including: euthyroid goiter, hypothyroidism, or hyperthyroidism. The natural history of AIT may be different in children but in all age groups, there appear to be genetic risk factors and environmental triggers that initiate thyroid autoimmunity. Areas covered: In this review, we summarize recent studies that investigate the genetics and environmental triggers believed to be involved in thyroid autoimmunity. We also discuss the approach and controversies in the treatment of children with AIT. Expert commentary: Much has been learned about the major roles for genetics, cytokines, regulatory lymphocytes, and environmental triggers in CLT but controversies remain.

Idioma originalEnglish (US)
Páginas (desde-hasta)129-142
Número de páginas14
PublicaciónExpert Review of Endocrinology and Metabolism
EstadoPublished - mar 4 2017
Publicado de forma externa

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism


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