Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used

David E. Harrison, Randy Strong, Peter Reifsnyder, Nadia Rosenthal, Ron Korstanje, Elizabeth Fernandez, Kevin Flurkey, Brett C. Ginsburg, Meredith D. Murrell, Martin A. Javors, Marisa Lopez-Cruzan, James F. Nelson, Bradley J. Willcox, Richard Allsopp, David M. Watumull, David G. Watumull, Gino Cortopassi, James L. Kirkland, Tamar Tchkonia, Young Geun ChoiMatthew J. Yousefzadeh, Paul D. Robbins, James R. Mitchell, Murat Acar, Ethan A. Sarnoski, Michael R. Bene, Adam Salmon, Navasuja Kumar, Richard A. Miller

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Profundice en los temas de investigación de 'Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used'. En conjunto forman una huella única.

Pharmacology, Toxicology and Pharmaceutical Science

Neuroscience

Biochemistry, Genetics and Molecular Biology