Assignment of retinoblastoma susceptibility gene to mouse chromosome 14

Chih Lin Hsieh; Wen Hwa Lee; Eva Y.H.P. Lee; Ann M. Killary; Peter A. Lalley; Susan L. Naylor

doi:10.1007/BF01534896

Assignment of retinoblastoma susceptibility gene to mouse chromosome 14

Chih Lin Hsieh, Wen Hwa Lee, Eva Y.H.P. Lee, Ann M. Killary, Peter A. Lalley, Susan L. Naylor

Department of Cell Systems & Anatomy

Resultado de la investigación: Article › revisión exhaustiva

13 Citas (Scopus)

Resumen

A human cDNA probe was used to screen a panel of mouse-Chinese hamster somatic cell hybrids to determine the chromosomal location of the retinoblastoma susceptibility gene (Rb-1)in mouse. The Rb-1 gene mapped to mouse chromosome 14. Thus, the retinoblastoma susceptibility gene is syntenic with esterase 10 (the mouse homolog of human esterase D). The chromosomal assignment of the mouse Rb-1 gene was further confirmed by using the same probe to study mouse-rat microcell hybrids. Since the human retinoblastoma susceptibility gene (RB1)along with the gene for esterase D is on chromosome 13q14, these data indicate this linkage group is conserved in man and mouse.

Idioma original	English (US)
Páginas (desde-hasta)	461-464
Número de páginas	4
Publicación	Somatic Cell and Molecular Genetics
Volumen	15
N.º	5
DOI	https://doi.org/10.1007/BF01534896
Estado	Published - sept 1989

ASJC Scopus subject areas

Genetics
Cell Biology

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title = "Assignment of retinoblastoma susceptibility gene to mouse chromosome 14",

abstract = "A human cDNA probe was used to screen a panel of mouse-Chinese hamster somatic cell hybrids to determine the chromosomal location of the retinoblastoma susceptibility gene (Rb-1)in mouse. The Rb-1 gene mapped to mouse chromosome 14. Thus, the retinoblastoma susceptibility gene is syntenic with esterase 10 (the mouse homolog of human esterase D). The chromosomal assignment of the mouse Rb-1 gene was further confirmed by using the same probe to study mouse-rat microcell hybrids. Since the human retinoblastoma susceptibility gene (RB1)along with the gene for esterase D is on chromosome 13q14, these data indicate this linkage group is conserved in man and mouse.",

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AU - Hsieh, Chih Lin

AU - Lee, Wen Hwa

AU - Lee, Eva Y.H.P.

AU - Killary, Ann M.

AU - Lalley, Peter A.

AU - Naylor, Susan L.

PY - 1989/9

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N2 - A human cDNA probe was used to screen a panel of mouse-Chinese hamster somatic cell hybrids to determine the chromosomal location of the retinoblastoma susceptibility gene (Rb-1)in mouse. The Rb-1 gene mapped to mouse chromosome 14. Thus, the retinoblastoma susceptibility gene is syntenic with esterase 10 (the mouse homolog of human esterase D). The chromosomal assignment of the mouse Rb-1 gene was further confirmed by using the same probe to study mouse-rat microcell hybrids. Since the human retinoblastoma susceptibility gene (RB1)along with the gene for esterase D is on chromosome 13q14, these data indicate this linkage group is conserved in man and mouse.

AB - A human cDNA probe was used to screen a panel of mouse-Chinese hamster somatic cell hybrids to determine the chromosomal location of the retinoblastoma susceptibility gene (Rb-1)in mouse. The Rb-1 gene mapped to mouse chromosome 14. Thus, the retinoblastoma susceptibility gene is syntenic with esterase 10 (the mouse homolog of human esterase D). The chromosomal assignment of the mouse Rb-1 gene was further confirmed by using the same probe to study mouse-rat microcell hybrids. Since the human retinoblastoma susceptibility gene (RB1)along with the gene for esterase D is on chromosome 13q14, these data indicate this linkage group is conserved in man and mouse.

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Assignment of retinoblastoma susceptibility gene to mouse chromosome 14

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