Assessment of long-term outcomes post living liver donation highlights the importance of scientific integrity when presenting transplant registry data

the NALLDIG Consortium*

Producción científica: Articlerevisión exhaustiva

Resumen

Living donor liver transplantation has expanded in recent years, particularly in North America. As experience with this procedure has matured over the last 25 years, centers are increasingly faced with potential living donors who are more medically complex. As donors move through the evaluation process, completing the informed consent process continues to be challenged by a paucity of granular data demonstrating long-term outcomes and overall safety specifically in the otherwise “healthy” living liver donor population. Two recently published studies examined long-term outcomes post-living liver donation using Korean registry data and reported similar results, with excellent overall survival when compared to appropriately matched controls. However, the authors of these studies were presented differently, with one reporting an alarmist view based on one aspect of a suboptimal analysis approach using an inappropriate comparator group. Herein, the North American Living Liver Donor Innovation Group (NALLDIG) consortium discusses these two studies and their potential impact on living liver donation in North America, ultimately highlighting the importance of scientific integrity in data presentation and dissemination when using transplant registry data.

Idioma originalEnglish (US)
Páginas (desde-hasta)1519-1522
Número de páginas4
PublicaciónAmerican Journal of Transplantation
Volumen22
N.º6
DOI
EstadoPublished - jun 2022

ASJC Scopus subject areas

  • Transplantation
  • Pharmacology (medical)
  • Immunology and Allergy

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