Assay of fluconazole by megabore capillary gas-liquid chromatography with nitrogen-selective detection

S. C. Harris; J. E. Wallace; G. Foulds; M. G. Rinaldi

doi:10.1128/AAC.33.5.714

Assay of fluconazole by megabore capillary gas-liquid chromatography with nitrogen-selective detection

S. C. Harris, J. E. Wallace, G. Foulds, M. G. Rinaldi

Resultado de la investigación: Article › revisión exhaustiva

50 Citas (Scopus)

Resumen

A megabore column gas-liquid chromatographic method which uses nitrogen-phosphorus detection was developed for the analysis of fluconazole in plasma, serum, cerebrospinal fluid, or urine. The assay was linear from 0.2 to 200 μg/ml and had an average coefficient of variation of 7%. The suitability of the assay for pharmacokinetic studies was demonstrated.

Idioma original	English (US)
Páginas (desde-hasta)	714-716
Número de páginas	3
Publicación	Antimicrobial agents and chemotherapy
Volumen	33
N.º	5
DOI	https://doi.org/10.1128/AAC.33.5.714
Estado	Published - 1989
Publicado de forma externa	Sí

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

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10.1128/AAC.33.5.714

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abstract = "A megabore column gas-liquid chromatographic method which uses nitrogen-phosphorus detection was developed for the analysis of fluconazole in plasma, serum, cerebrospinal fluid, or urine. The assay was linear from 0.2 to 200 μg/ml and had an average coefficient of variation of 7%. The suitability of the assay for pharmacokinetic studies was demonstrated.",

author = "Harris, {S. C.} and Wallace, {J. E.} and G. Foulds and Rinaldi, {M. G.}",

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Assay of fluconazole by megabore capillary gas-liquid chromatography with nitrogen-selective detection

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