The antithrombin III-heparin cofactor activity of 65 baboons and 130 healthy human subjects was measured. The results indicate that antithrombin III-heparin cofactor activity is significantly lower in baboons than in humans. The increased activity of the coagulation system of baboon is coupled with decreased antithrombin III-heparin cofactor activity. In humans each of these changes is associated with increased risk of thrombosis, but the baboon has a very low risk of developing thrombosis. Other factors probably balance the coagulation-coagulation inhibition systems in baboons.
|Idioma original||English (US)|
|Número de páginas||8|
|Estado||Published - abr 1978|
|Publicado de forma externa||Sí|
ASJC Scopus subject areas
- Animal Science and Zoology