An expeditious approach to access 2-arylimidazo[1,2-a]pyridin-3-ol from 2-amino pyridine through a novel Petasis based cascade reaction

Yuanxiang Wang; Biswajit Saha; Fang Li; Brendan Frett; Hong Yu Li

doi:10.1016/j.tetlet.2013.12.018

An expeditious approach to access 2-arylimidazo[1,2-a]pyridin-3-ol from 2-amino pyridine through a novel Petasis based cascade reaction

Yuanxiang Wang
, Biswajit Saha
, Fang Li
, Brendan Frett
, Hong Yu Li

Producción científica: Article › revisión exhaustiva

21 Citas (Scopus)

Resumen

An expeditious cascade protocol for the synthesis of functionalized imidazo[1,2-a]pyridin-3-ols was developed based on the Petasis reaction. With the availability of commercial reagents and high efficiency in expanding molecule diversity, this methodology is superior to the existing procedures for the synthesis of imidazo-pyridin-3-ol analogues.

Idioma original	English (US)
Páginas (desde-hasta)	1281-1284
Número de páginas	4
Publicación	Tetrahedron Letters
Volumen	55
N.º	7
DOI	https://doi.org/10.1016/j.tetlet.2013.12.018
Estado	Published - feb 12 2014
Publicado de forma externa	Sí

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

Acceder al documento

10.1016/j.tetlet.2013.12.018

Otros archivos y enlaces

Citar esto

@article{69d4dadcb37942b892c39a1619d7bb53,

title = "An expeditious approach to access 2-arylimidazo[1,2-a]pyridin-3-ol from 2-amino pyridine through a novel Petasis based cascade reaction",

abstract = "An expeditious cascade protocol for the synthesis of functionalized imidazo[1,2-a]pyridin-3-ols was developed based on the Petasis reaction. With the availability of commercial reagents and high efficiency in expanding molecule diversity, this methodology is superior to the existing procedures for the synthesis of imidazo-pyridin-3-ol analogues.",

keywords = "2-Arylimidazo[1,2-a]pyridine-3-ol, Cascade reaction, MCR, Petasis reaction",

author = "Yuanxiang Wang and Biswajit Saha and Fang Li and Brendan Frett and Li, \{Hong Yu\}",

year = "2014",

month = feb,

day = "12",

doi = "10.1016/j.tetlet.2013.12.018",

language = "English (US)",

volume = "55",

pages = "1281--1284",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Ltd",

number = "7",

}

TY - JOUR

T1 - An expeditious approach to access 2-arylimidazo[1,2-a]pyridin-3-ol from 2-amino pyridine through a novel Petasis based cascade reaction

AU - Wang, Yuanxiang

AU - Saha, Biswajit

AU - Li, Fang

AU - Frett, Brendan

AU - Li, Hong Yu

PY - 2014/2/12

Y1 - 2014/2/12

N2 - An expeditious cascade protocol for the synthesis of functionalized imidazo[1,2-a]pyridin-3-ols was developed based on the Petasis reaction. With the availability of commercial reagents and high efficiency in expanding molecule diversity, this methodology is superior to the existing procedures for the synthesis of imidazo-pyridin-3-ol analogues.

AB - An expeditious cascade protocol for the synthesis of functionalized imidazo[1,2-a]pyridin-3-ols was developed based on the Petasis reaction. With the availability of commercial reagents and high efficiency in expanding molecule diversity, this methodology is superior to the existing procedures for the synthesis of imidazo-pyridin-3-ol analogues.

KW - 2-Arylimidazo[1,2-a]pyridine-3-ol

KW - Cascade reaction

KW - MCR

KW - Petasis reaction

UR - https://www.scopus.com/pages/publications/84893779109

UR - https://www.scopus.com/pages/publications/84893779109#tab=citedBy

U2 - 10.1016/j.tetlet.2013.12.018

DO - 10.1016/j.tetlet.2013.12.018

M3 - Article

AN - SCOPUS:84893779109

SN - 0040-4039

VL - 55

SP - 1281

EP - 1284

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 7

ER -

An expeditious approach to access 2-arylimidazo[1,2-a]pyridin-3-ol from 2-amino pyridine through a novel Petasis based cascade reaction

Resumen

ASJC Scopus subject areas

Acceder al documento

Otros archivos y enlaces

Huella

Citar esto