An editorial update: What level of blood pressure control in chronic kidney disease?

Several recent studies have tried to characterize the effects of a lower-than-usual target blood pressure on progression of nondiabetic kidney disease. An observational study, the Modification of Diet in Renal Disease Study, showed long-term benefit. The randomized African-American Study of Kidney Disease and Hypertension showed no benefit, nor did the recently published Ramipril Efficacy in Nephropathy 2 Trial. Here's our take on these conflicting study results.