Adult-onset Rasmussen's Syndrome with associated cortical dysplasia

C. Ákos Szabó, Rachel Garvin, Shaheryar Hafeez, Ali Seifi, Linda Leary, Ratna Bhavaraju-Sanka, James M. Henry, Alex M. Papanastassiou

Producción científica: Articlerevisión exhaustiva

Resumen

We describe a 23-year-old woman with previous right temporal lobe surgeries for underlying cortical dysplasia, presenting with drug-resistant right hemispheric seizures and epilepsia partialis continua (EPC). After anti-seizure medication adjustments, she developed focal status epilepticus with progressive EEG and neuroimaging changes. Cerebrospinal fluid and serum autoimmune panels were negative except for an elevated serum acetylcholine-receptor antibody titer, but she underwent immunosuppressive therapy. Stereotactic-EEG evaluation demonstrated multifocal independent ictal patterns in the right hemisphere. Rasmussen's Syndrome was confirmed by brain biopsy, and a hemispherectomy was performed. This patient demonstrates the rare association of adult-onset EPC with cortical dysplasia, precipitously evolving into Rasmussen's Syndrome.

Idioma originalEnglish (US)
Páginas (desde-hasta)54-57
Número de páginas4
PublicaciónEpilepsy and Behavior Case Reports
Volumen11
DOI
EstadoPublished - ene 1 2019

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Behavioral Neuroscience

Huella

Profundice en los temas de investigación de 'Adult-onset Rasmussen's Syndrome with associated cortical dysplasia'. En conjunto forman una huella única.

Citar esto