Adenine phosphoribosyl transferase polymorphism in baboons

John L. VandeBerg; Mary Jo Aivaliotis

doi:10.1007/BF00569323

Adenine phosphoribosyl transferase polymorphism in baboons

John L. VandeBerg, Mary Jo Aivaliotis

Resultado de la investigación: Article › revisión exhaustiva

Resumen

Two allelic isozymes of adenine phosphoribosyl transferase (APRT) were detected by starch gel electrophoresis of baboon hemolysates. Extensive family data verified autosomal codominant inheritance. The gene frequencies of five subspecies of baboons differed significantly. The activity of erythrocyte APRT is sufficiently high to enable the use of this enzyme as a sensitive marker for assessing chimerism in research involving bone marrow transplantation.

Idioma original	English (US)
Páginas (desde-hasta)	331-337
Número de páginas	7
Publicación	Biochemical Genetics
Volumen	30
N.º	7-8
DOI	https://doi.org/10.1007/BF00569323
Estado	Published - ago 1992

ASJC Scopus subject areas

Ecology, Evolution, Behavior and Systematics
Biochemistry
Molecular Biology
Genetics

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10.1007/BF00569323

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title = "Adenine phosphoribosyl transferase polymorphism in baboons",

abstract = "Two allelic isozymes of adenine phosphoribosyl transferase (APRT) were detected by starch gel electrophoresis of baboon hemolysates. Extensive family data verified autosomal codominant inheritance. The gene frequencies of five subspecies of baboons differed significantly. The activity of erythrocyte APRT is sufficiently high to enable the use of this enzyme as a sensitive marker for assessing chimerism in research involving bone marrow transplantation.",

keywords = "bone marrow transplantation, genetic marker, isozyme, paternity testing, primates",

author = "VandeBerg, {John L.} and Aivaliotis, {Mary Jo}",

year = "1992",

month = aug,

doi = "10.1007/BF00569323",

language = "English (US)",

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pages = "331--337",

journal = "Biochemical Genetics",

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AU - VandeBerg, John L.

AU - Aivaliotis, Mary Jo

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AB - Two allelic isozymes of adenine phosphoribosyl transferase (APRT) were detected by starch gel electrophoresis of baboon hemolysates. Extensive family data verified autosomal codominant inheritance. The gene frequencies of five subspecies of baboons differed significantly. The activity of erythrocyte APRT is sufficiently high to enable the use of this enzyme as a sensitive marker for assessing chimerism in research involving bone marrow transplantation.

KW - bone marrow transplantation

KW - genetic marker

KW - isozyme

KW - paternity testing

KW - primates

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JF - Biochemical Genetics

IS - 7-8

ER -

Adenine phosphoribosyl transferase polymorphism in baboons

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