Activation of WEE1 confers resistance to PI3K inhibition in glioblastoma

Medicine and Dentistry

• Phosphoinositide 3-Kinase 81%
• Glioblastoma 45%
• Cells 36%
• Programmed Cell Death 27%
• Protein 18%
• Xenograft 18%
• Tumor Progression 18%
• Cell Division 18%
• Neoplasm 9%
• Carcinogenesis 9%
• Signal Transduction 9%
• Cancer Cell 9%
• Ganglioglioma 9%
• Protein P53 9%
• Cell Proliferation 9%
• Immunohistochemistry 9%
• Phosphotransferase 9%
• Blood Brain Barrier 9%
• Kinase Signaling 9%
• Blotting 9%
• Mitosis 9%
• Development 9%
• Caspase 3 9%
• Phosphoinositide 3-Kinase Inhibitor 9%
• Poly ADP Ribose Polymerase 9%
• Lipocortin 5 9%
• Bioluminescence 9%
• Gene 9%
• Assay 9%
• Therapeutic Procedure 9%
• Tissues 9%
• Targeted Therapy 9%
• Patient 9%

Biochemistry, Genetics and Molecular Biology

• Kinase 100%
• Phosphatidylinositol 90%
• Apoptosis 18%
• Cell Division 18%
• Growth 18%
• Protein 18%
• Signal Transduction 9%
• Cancer Cell 9%
• Nested Gene 9%
• P53 9%
• Cell Proliferation 9%
• Development 9%
• Mitosis 9%
• Blood Brain Barrier 9%
• Cell Death 9%
• Caspase 3 9%
• Staining 9%
• Bioluminescence Imaging 9%
• Poly ADP Ribose Polymerase 9%
• Mitotic Catastrophe 9%
• Annexin 9%

Pharmacology, Toxicology and Pharmaceutical Science

• Phosphatidylinositol 3 Kinase 81%
• Glioblastoma 45%
• Protein 18%
• Tumor Growth 18%
• Neoplasm 9%
• Carcinogenesis 9%
• Phosphotransferase 9%
• Blood-Brain Barrier 9%
• Glioma 9%
• Phosphatidylinositol 3 Kinase Inhibitor 9%
• Protein P53 9%
• Caspase 3 9%
• Lipocortin 5 9%
• Nicotinamide Adenine Dinucleotide Adenosine Diphosphate Ribosyltransferase 9%