A subpopulation of cultured avian neural crest cells has transient neurogenic potential

Kristine S. Vogel, James A. Weston

Producción científica: Articlerevisión exhaustiva

67 Citas (Scopus)

Resumen

Neural crest cells of vertebrate embryos produce neurons, glia, pigment cells, and connective tissue in vivo and in vitro. To test the developmental potential of apparently undifferentiated crest cells, we have used the monoclonal antibody A2B5, which recognizes a cell surface glycolipid characteristic of neurons, to identify and immunoablate a subpopulation of cultured avian neural crest cells with a neuronal phenotype. Our results indicate that a limited neurogenic precursor subpopulation is present in cultures of avian neural crest cells and that the fate of this subpopulation can be influenced by environmental conditions arising when dispersal of neural crest cells is delayed.

Idioma originalEnglish (US)
Páginas (desde-hasta)569-577
Número de páginas9
PublicaciónNeuron
Volumen1
N.º7
DOI
EstadoPublished - sept 1988
Publicado de forma externa

ASJC Scopus subject areas

  • General Neuroscience

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