A random signal model for cDNA microarrays

Y. Balagurunathan, E. R. Dougherty, Y. Chen, M. L. Bitter, J. M. Trent

Producción científica: Articlerevisión exhaustiva


The images resulting from cDNA microarrays are highly random. There are many aspects to this randomness, including spot size, shape, intensity, uniformity, and circularity, as well as both foreground and background noise. This paper presents a random model for the generation of microarray images. The model is complicated and contains over twenty parameters. It can be used to test microarray imaging algorithms and to simulate the effects of various dependencies within the image formation process.

Idioma originalEnglish (US)
Páginas (desde-hasta)163-170
Número de páginas8
PublicaciónProceedings of SPIE-The International Society for Optical Engineering
EstadoPublished - 2001
Publicado de forma externa

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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