A polymorphic DNA marker genetically linked to Huntington's disease

James F. Gusella; Nancy S. Wexler; P. Michael Conneally; Susan L. Naylor; Mary Anne Anderson; Rudolph E. Tanzi; Paul C. Watkins; Kathleen Ottina; Margaret R. Wallace; Alan Y. Sakaguchi; Anne B. Young; Ira Shoulson; Ernesto Bonilla; Joseph B. Martin

doi:10.1038/306234a0

A polymorphic DNA marker genetically linked to Huntington's disease

James F. Gusella
, Nancy S. Wexler
, P. Michael Conneally
, Susan L. Naylor
, Mary Anne Anderson
, Rudolph E. Tanzi
, Paul C. Watkins
, Kathleen Ottina
, Margaret R. Wallace
, Alan Y. Sakaguchi
, Anne B. Young
, Ira Shoulson
, Ernesto Bonilla
, Joseph B. Martin

Producción científica: Article › revisión exhaustiva

1809 Citas (Scopus)

Resumen

Family studies show that the Huntington's disease gene is linked to a polymorphic DNA marker that maps to human chromosome 4. The chromosomal localization of the Huntington's disease gene is the first step in using recombinant DNA technology to identify the primary genetic defect in this disorder.

Idioma original	English (US)
Páginas (desde-hasta)	234-238
Número de páginas	5
Publicación	Nature
Volumen	306
N.º	5940
DOI	https://doi.org/10.1038/306234a0
Estado	Published - 1983
Publicado de forma externa	Sí

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10.1038/306234a0

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title = "A polymorphic DNA marker genetically linked to Huntington's disease",

abstract = "Family studies show that the Huntington's disease gene is linked to a polymorphic DNA marker that maps to human chromosome 4. The chromosomal localization of the Huntington's disease gene is the first step in using recombinant DNA technology to identify the primary genetic defect in this disorder.",

author = "Gusella, \{James F.\} and Wexler, \{Nancy S.\} and Conneally, \{P. Michael\} and Naylor, \{Susan L.\} and Anderson, \{Mary Anne\} and Tanzi, \{Rudolph E.\} and Watkins, \{Paul C.\} and Kathleen Ottina and Wallace, \{Margaret R.\} and Sakaguchi, \{Alan Y.\} and Young, \{Anne B.\} and Ira Shoulson and Ernesto Bonilla and Martin, \{Joseph B.\}",

year = "1983",

doi = "10.1038/306234a0",

language = "English (US)",

volume = "306",

pages = "234--238",

journal = "Nature",

issn = "0028-0836",

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number = "5940",

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T1 - A polymorphic DNA marker genetically linked to Huntington's disease

AU - Gusella, James F.

AU - Wexler, Nancy S.

AU - Conneally, P. Michael

AU - Naylor, Susan L.

AU - Anderson, Mary Anne

AU - Tanzi, Rudolph E.

AU - Watkins, Paul C.

AU - Ottina, Kathleen

AU - Wallace, Margaret R.

AU - Sakaguchi, Alan Y.

AU - Young, Anne B.

AU - Shoulson, Ira

AU - Bonilla, Ernesto

AU - Martin, Joseph B.

PY - 1983

Y1 - 1983

N2 - Family studies show that the Huntington's disease gene is linked to a polymorphic DNA marker that maps to human chromosome 4. The chromosomal localization of the Huntington's disease gene is the first step in using recombinant DNA technology to identify the primary genetic defect in this disorder.

AB - Family studies show that the Huntington's disease gene is linked to a polymorphic DNA marker that maps to human chromosome 4. The chromosomal localization of the Huntington's disease gene is the first step in using recombinant DNA technology to identify the primary genetic defect in this disorder.

UR - https://www.scopus.com/pages/publications/0021028244

UR - https://www.scopus.com/pages/publications/0021028244#tab=citedBy

U2 - 10.1038/306234a0

DO - 10.1038/306234a0

M3 - Article

C2 - 6316146

AN - SCOPUS:0021028244

SN - 0028-0836

VL - 306

SP - 234

EP - 238

JO - Nature

JF - Nature

IS - 5940

ER -

A polymorphic DNA marker genetically linked to Huntington's disease

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