Description
Figure S3. CRISPR/Cas9 mediated HDACs inhibition and evaluation of tumor cell growth inhibition in eRMS. (a-e) CRISPR/Cas9 screen for viability of selected HDACs (HDAC1-2 & HDAC10-11) excision by CRISPR in murine eRMS. (f) Q-PCR of murine eRMS U57810 for the expression of myogenic markers of differentiation in vitro. Data normalized to GAPDH expression. Gene expression was quantified using 2â ^dCt method. Myogenin (MYOG), Myoblast determination protein 1 (MyoD) and Myoglobin (Mb). (TIF 2070 kb)
| Datos disponibles | 2019 |
|---|---|
| Editor | Figshare |