M. G. Rinaldi

Research output: Contribution to journalReview articlepeer-review

93 Scopus citations


Zygomycosis represents an excellent example of an opportunistic fungal infection that generally occurs in the debilitated, immunocompromised, or acidotic host. Infections are usually fulminant, with etiologic agents exhibiting predilection for invasion of blood vessels with resultant infarction and necrosis. The spectrum of agents capable of inciding zygomycosis has broadened and the incidence has increased in contemporary medicine. Nevertheless, an increased index of suspicion, better mycological acumen, aggressive surgical debridement of diseased tissue, and prompt therapy with amphotericin B have rendered substantial improvement in the prognosis of an otherwise fatal infectious disease. Rapid and accurate diagnostic techniques and the availability of less toxic, efficacious antifungal agents should be sought after goals for the enhanced management of zygomycosis.

Original languageEnglish (US)
Pages (from-to)19-41
Number of pages23
JournalInfectious disease clinics of North America
Issue number1
StatePublished - Mar 1989

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases


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