Zidovudine and cytomegalovirus retinitis.

John E Carter, A. R. Shuster

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A 38-year-old bisexual man with acquired immunodeficiency syndrome (AIDS) who was being treated with oral acyclovir for herpetic stomatitis had a history of blurred vision OS that was diagnosed as cytomegalovirus retinitis. The patient refused ganciclovir administration. Two additional lesions developed OS in the succeeding four months. All clinical evidence of active retinitis cleared after zidovudine was administered, and the patient has remained free of any clinically active retinal lesions for 28 months while continuing to receive acyclovir and zidovudine. Although ganciclovir and foscarnet are the drugs of choice to treat cytomegalovirus retinitis, this observation may be fortuitous for patients whose other AIDS manifestations suggest using zidovudine rather than ganciclovir or for patients whose cytomegalovirus retinitis appears to be resistant to agents currently used to treat this infection.

Original languageEnglish (US)
Pages (from-to)186-189
Number of pages4
JournalAnnals of Ophthalmology
Volume24
Issue number5
StatePublished - May 1992

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Cytomegalovirus Retinitis
Zidovudine
Ganciclovir
Acyclovir
Acquired Immunodeficiency Syndrome
Herpetic Stomatitis
Foscarnet
Retinitis
Infection
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Zidovudine and cytomegalovirus retinitis. / Carter, John E; Shuster, A. R.

In: Annals of Ophthalmology, Vol. 24, No. 5, 05.1992, p. 186-189.

Research output: Contribution to journalArticle

Carter, JE & Shuster, AR 1992, 'Zidovudine and cytomegalovirus retinitis.', Annals of Ophthalmology, vol. 24, no. 5, pp. 186-189.
Carter, John E ; Shuster, A. R. / Zidovudine and cytomegalovirus retinitis. In: Annals of Ophthalmology. 1992 ; Vol. 24, No. 5. pp. 186-189.
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