TY - JOUR
T1 - Youth-onset type 2 diabetes consensus report
T2 - Current status, challenges, and priorities
AU - Nadeau, Kristen J.
AU - Anderson, Barbara J.
AU - Berg, Erika G.
AU - Chiang, Jane L.
AU - Chou, Hubert
AU - Copeland, Kenneth C.
AU - Hannon, Tamara S.
AU - Huang, Terry T.K.
AU - Lynch, Jane L.
AU - Powell, Jeff
AU - Sellers, Elizabeth
AU - Tamborlane, William V.
AU - Zeitler, Philip
N1 - Publisher Copyright:
© 2016 by the American Diabetes Association.
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Type 2 diabetes is a significant and increasing burden in adolescents and young adults. Clear strategies for research, prevention, and treatment of the disease in these vulnerable patients are needed. Evidence suggests that type 2 diabetes in children is different not only from type 1 but also from type 2 diabetes in adults. Understanding the unique pathophysiology of type 2 diabetes in youth, as well as the risk of complications and the psychosocial impact, will enable industry, academia, funding agencies, advocacy groups, and regulators to collectively evaluate both current and future research, treatment, and prevention approaches. This Consensus Report characterizes type 2 diabetes in children, evaluates the fundamental differences between childhood and adult disease, describes the current therapeutic options, and discusses challenges to and approaches for developing new treatments.
AB - Type 2 diabetes is a significant and increasing burden in adolescents and young adults. Clear strategies for research, prevention, and treatment of the disease in these vulnerable patients are needed. Evidence suggests that type 2 diabetes in children is different not only from type 1 but also from type 2 diabetes in adults. Understanding the unique pathophysiology of type 2 diabetes in youth, as well as the risk of complications and the psychosocial impact, will enable industry, academia, funding agencies, advocacy groups, and regulators to collectively evaluate both current and future research, treatment, and prevention approaches. This Consensus Report characterizes type 2 diabetes in children, evaluates the fundamental differences between childhood and adult disease, describes the current therapeutic options, and discusses challenges to and approaches for developing new treatments.
UR - http://www.scopus.com/inward/record.url?scp=84986224381&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84986224381&partnerID=8YFLogxK
U2 - 10.2337/dc16-1066
DO - 10.2337/dc16-1066
M3 - Article
C2 - 27486237
AN - SCOPUS:84986224381
SN - 0149-5992
VL - 39
SP - 1635
EP - 1642
JO - Diabetes care
JF - Diabetes care
IS - 9
ER -