Abstract
An in-frame deletion of the yopH gene in Yersinia pestis CO92 attenuates virulence in both bubonic and pneumonic plague models. When it is used as a live, attenuated vaccine, CO92ΔyopH provides a high degree of protection from parental and respiratory challenge with Y. pestis CO92.
Original language | English (US) |
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Pages (from-to) | 1235-1238 |
Number of pages | 4 |
Journal | Clinical and Vaccine Immunology |
Volume | 14 |
Issue number | 9 |
DOIs | |
State | Published - Sep 2007 |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Clinical Biochemistry
- Microbiology (medical)