What initiates chemical intolerance?

Shahir Masri, Claudia Miller

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Toxicant-induced loss of tolerance (TILT) is a two-stage disease mechanism that includes initiation, in which a chemical exposure leads to onset of TILT, and triggering, in which subsequent exposures to a variety of chemicals elicit symptoms. Little is known about initiating events and underlying causes of TILT. This analysis reviews several major exposure events that initiated TILT. Examining these events collectively enables a better understanding of the exposures that may initiate TILT, in turn informing exposed individuals, physicians, and policymakers on how best to protect health.

Original languageEnglish (US)
Title of host publication15th Conference of the International Society of Indoor Air Quality and Climate, INDOOR AIR 2018
PublisherInternational Society of Indoor Air Quality and Climate
ISBN (Electronic)9781713826514
StatePublished - 2018
Externally publishedYes
Event15th Conference of the International Society of Indoor Air Quality and Climate, INDOOR AIR 2018 - Philadelphia, United States
Duration: Jul 22 2018Jul 27 2018

Publication series

Name15th Conference of the International Society of Indoor Air Quality and Climate, INDOOR AIR 2018

Conference

Conference15th Conference of the International Society of Indoor Air Quality and Climate, INDOOR AIR 2018
Country/TerritoryUnited States
CityPhiladelphia
Period7/22/187/27/18

Keywords

  • Chemical intolerance
  • Chemical sensitivity
  • Gulf war illness
  • Sick building syndrome
  • TILT

ASJC Scopus subject areas

  • Pollution

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