Waist circumference and BMI in relation to serum high sensitivity c-reactive protein (hs-CRP) in Cuban Americans with and without type 2 diabetes

Fatma G. Huffman; Suzanne Whisner; Gustavo G. Zarini; Subrata Nath

doi:10.3390/ijerph7030842

Waist circumference and BMI in relation to serum high sensitivity c-reactive protein (hs-CRP) in Cuban Americans with and without type 2 diabetes

Fatma G. Huffman, Suzanne Whisner, Gustavo G. Zarini, Subrata Nath

Division of Nephrology/Renal Diseases

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

Relationship between high-sensitivity C-reactive protein (hs-CRP) and adiposity by diabetes status and gender in Cuban-Americans with and without type 2 diabetes (T2D) was studied. Adult subjects, 226 females, 129 males participated in a case control, single time point study. Subjects with T2D were older, had higher waist circumference (WC) and body mass index (BMI). WC and BMI were associated with ln hs-CRP (P < 0.001). An interaction with diabetes status was found for BMI (P = 0.037). Gender showed a strong relationship with ln hs-CRP (P < 0.001), which was moderated by diabetes status. Only males without diabetes exhibited a significant relationship for both WC and BMI with ln hs-CRP. In this sample of Cuban-Americans, WC and BMI had stronger associations with ln hs-CRP but not with diabetes status. Obesity prevention and controlling for CRP levels may be necessary to eliminate its contributions to develop diabetes and cardiovascular disease (CVD).

Original language	English (US)
Pages (from-to)	842-852
Number of pages	11
Journal	International Journal of Environmental Research and Public Health
Volume	7
Issue number	3
DOIs	https://doi.org/10.3390/ijerph7030842
State	Published - Mar 2010

Keywords

Body mass index
High-sensitivity c-reactive protein
Type 2 diabetes
Waist circumference

ASJC Scopus subject areas

Pollution
Public Health, Environmental and Occupational Health
Health, Toxicology and Mutagenesis

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10.3390/ijerph7030842

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Waist circumference and BMI in relation to serum high sensitivity c-reactive protein (hs-CRP) in Cuban Americans with and without type 2 diabetes. / Huffman, Fatma G.; Whisner, Suzanne; Zarini, Gustavo G. et al.
In: International Journal of Environmental Research and Public Health, Vol. 7, No. 3, 03.2010, p. 842-852.

Research output: Contribution to journal › Article › peer-review

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abstract = "Relationship between high-sensitivity C-reactive protein (hs-CRP) and adiposity by diabetes status and gender in Cuban-Americans with and without type 2 diabetes (T2D) was studied. Adult subjects, 226 females, 129 males participated in a case control, single time point study. Subjects with T2D were older, had higher waist circumference (WC) and body mass index (BMI). WC and BMI were associated with ln hs-CRP (P < 0.001). An interaction with diabetes status was found for BMI (P = 0.037). Gender showed a strong relationship with ln hs-CRP (P < 0.001), which was moderated by diabetes status. Only males without diabetes exhibited a significant relationship for both WC and BMI with ln hs-CRP. In this sample of Cuban-Americans, WC and BMI had stronger associations with ln hs-CRP but not with diabetes status. Obesity prevention and controlling for CRP levels may be necessary to eliminate its contributions to develop diabetes and cardiovascular disease (CVD).",

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AU - Nath, Subrata

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AB - Relationship between high-sensitivity C-reactive protein (hs-CRP) and adiposity by diabetes status and gender in Cuban-Americans with and without type 2 diabetes (T2D) was studied. Adult subjects, 226 females, 129 males participated in a case control, single time point study. Subjects with T2D were older, had higher waist circumference (WC) and body mass index (BMI). WC and BMI were associated with ln hs-CRP (P < 0.001). An interaction with diabetes status was found for BMI (P = 0.037). Gender showed a strong relationship with ln hs-CRP (P < 0.001), which was moderated by diabetes status. Only males without diabetes exhibited a significant relationship for both WC and BMI with ln hs-CRP. In this sample of Cuban-Americans, WC and BMI had stronger associations with ln hs-CRP but not with diabetes status. Obesity prevention and controlling for CRP levels may be necessary to eliminate its contributions to develop diabetes and cardiovascular disease (CVD).

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Waist circumference and BMI in relation to serum high sensitivity c-reactive protein (hs-CRP) in Cuban Americans with and without type 2 diabetes

Abstract

Keywords

ASJC Scopus subject areas

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