Waist circumference and BMI in relation to serum high sensitivity c-reactive protein (hs-CRP) in Cuban Americans with and without type 2 diabetes

Fatma G. Huffman, Suzanne Whisner, Gustavo G. Zarini, Subrata Nath

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Relationship between high-sensitivity C-reactive protein (hs-CRP) and adiposity by diabetes status and gender in Cuban-Americans with and without type 2 diabetes (T2D) was studied. Adult subjects, 226 females, 129 males participated in a case control, single time point study. Subjects with T2D were older, had higher waist circumference (WC) and body mass index (BMI). WC and BMI were associated with ln hs-CRP (P < 0.001). An interaction with diabetes status was found for BMI (P = 0.037). Gender showed a strong relationship with ln hs-CRP (P < 0.001), which was moderated by diabetes status. Only males without diabetes exhibited a significant relationship for both WC and BMI with ln hs-CRP. In this sample of Cuban-Americans, WC and BMI had stronger associations with ln hs-CRP but not with diabetes status. Obesity prevention and controlling for CRP levels may be necessary to eliminate its contributions to develop diabetes and cardiovascular disease (CVD).

Original languageEnglish (US)
Pages (from-to)842-852
Number of pages11
JournalInternational Journal of Environmental Research and Public Health
Volume7
Issue number3
DOIs
StatePublished - Mar 2010

Keywords

  • Body mass index
  • High-sensitivity c-reactive protein
  • Type 2 diabetes
  • Waist circumference

ASJC Scopus subject areas

  • Pollution
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

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