Abstract
The low-molecular peptide fractions are obtained from the brain of experimental and control animals by the method which includes sedimentation of high-molecular compounds and gel-filtration on Sephadex G-10. Ischemia of the rat brain sharply changes the amino acidic composition of the isolated peptide fractions. An inhibitory effect of the studied fractions on the activity of DNA-dependent RNA polymerase as well as their effect on the heat denaturation of exogenous DNA are established.
| Translated title of the contribution | Isolation and characteristics of peptide fractions from the rat brain in ischemia |
|---|---|
| Original language | Russian |
| Pages (from-to) | 13-17 |
| Number of pages | 5 |
| Journal | Ukrainski¿ biokhimicheski¿ zhurnal |
| Volume | 57 |
| Issue number | 6 |
| State | Published - Nov 1985 |
| Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry