Virulence of Curvularia in a murine model

Katihuska Paredes, Javier Capilla, Deanna A. Sutton, Emilio Mayayo, Annette W. Fothergill, Josep Guarro

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

We have evaluated the virulence of two clinically relevant species of Curvularia; Curvularia spicifera and C. hawaiiensis, using an experimental model of disseminated infection in immunocompromised mice. Several inocula were tested over a range 1 × 103-1 × 106 colony-forming units/animal. Both species had a similar behaviour, producing a high mortality. Tissue burden and histopathology studies demonstrated that lung was the organ most affected.

Original languageEnglish (US)
Pages (from-to)512-515
Number of pages4
JournalMycoses
Volume56
Issue number5
DOIs
StatePublished - Sep 2013

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Keywords

  • Animal model
  • Bipolaris
  • Curvularia
  • Fungal infections

ASJC Scopus subject areas

  • Dermatology
  • Infectious Diseases

Cite this

Paredes, K., Capilla, J., Sutton, D. A., Mayayo, E., Fothergill, A. W., & Guarro, J. (2013). Virulence of Curvularia in a murine model. Mycoses, 56(5), 512-515. https://doi.org/10.1111/myc.12064