Viral assembly of oriented quantum dot nanowires

Chuanbin Mao, Christine E. Flynn, Andrew Hayhurst, Rozamond Sweeney, Jifa Qi, George Georgiou, Brent Iverson, Angela M. Belcher

    Research output: Contribution to journalArticle

    390 Citations (Scopus)

    Abstract

    The highly organized structure of M13 bacteriophage was used as an evolved biological template for the nucleation and orientation of semiconductor nanowires. To create this organized template, peptides were selected by using a plll phage display library for their ability to nucleate ZnS or CdS nanocrystals. The successful peptides were expressed as pvIII fusion proteins into the crystalline capsid of the virus. The engineered viruses were exposed to semiconductor precursor solutions, and the resultant nanocrystals that were templated along the viruses to form nanowires were extensively characterized by using high-resolution analytical electron microscopy and photoluminescence. ZnS nanocrystals were well crystallized on the viral capsid in a hexagonal wurtzite or a cubic zinc blende structure, depending on the peptide expressed on the viral capsid. Electron diffraction patterns showed single-crystal type behavior from a polynanocrystalline area of the nanowire formed, suggesting that the nanocrystals on the virus were preferentially oriented with their [001] perpendicular to the viral surface. Peptides that specifically directed CdS nanocrystal growth were also engineered into the viral capsid to create wurtzite CdS virus-based nanowires. Lastly, heterostructured nucleation was achieved with a dual-peptide virus engineered to express two distinct peptides within the same viral capsid. This work represents a genetically controlled biological synthesis route to a semiconductor nanoscale heterostructure.

    Original languageEnglish (US)
    Pages (from-to)6946-6951
    Number of pages6
    JournalProceedings of the National Academy of Sciences of the United States of America
    Volume100
    Issue number12
    DOIs
    StatePublished - Jun 10 2003

    Fingerprint

    Nanowires
    Virus Assembly
    Quantum Dots
    Capsid
    Nanoparticles
    Viruses
    Peptides
    Semiconductors
    Bacteriophage M13
    Bacteriophages
    Libraries
    Zinc
    Electron Microscopy
    Electrons
    Growth

    ASJC Scopus subject areas

    • Genetics
    • General

    Cite this

    Mao, C., Flynn, C. E., Hayhurst, A., Sweeney, R., Qi, J., Georgiou, G., ... Belcher, A. M. (2003). Viral assembly of oriented quantum dot nanowires. Proceedings of the National Academy of Sciences of the United States of America, 100(12), 6946-6951. https://doi.org/10.1073/pnas.0832310100

    Viral assembly of oriented quantum dot nanowires. / Mao, Chuanbin; Flynn, Christine E.; Hayhurst, Andrew; Sweeney, Rozamond; Qi, Jifa; Georgiou, George; Iverson, Brent; Belcher, Angela M.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, No. 12, 10.06.2003, p. 6946-6951.

    Research output: Contribution to journalArticle

    Mao, C, Flynn, CE, Hayhurst, A, Sweeney, R, Qi, J, Georgiou, G, Iverson, B & Belcher, AM 2003, 'Viral assembly of oriented quantum dot nanowires', Proceedings of the National Academy of Sciences of the United States of America, vol. 100, no. 12, pp. 6946-6951. https://doi.org/10.1073/pnas.0832310100
    Mao, Chuanbin ; Flynn, Christine E. ; Hayhurst, Andrew ; Sweeney, Rozamond ; Qi, Jifa ; Georgiou, George ; Iverson, Brent ; Belcher, Angela M. / Viral assembly of oriented quantum dot nanowires. In: Proceedings of the National Academy of Sciences of the United States of America. 2003 ; Vol. 100, No. 12. pp. 6946-6951.
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