Abstract
This Hot Topics review, the first in a projected annual series, discusses those articles, published in the last year, which seem likely to have a major impact on our understanding of the aging process in mammals and the links between aging and late-life illnesses. The year's highlights include studies of oxidation damage in the very-long-lived naked mole-rat, and of caloric restriction in monkeys, humans, and growth hormone-unresponsive mice. Two studies of resveratrol, one showing its ability to extend lifespan in a short-lived fish, the other demonstrating beneficial effects in mice subjected to a diet high in fat, may well be harbingers of a parade of intervention studies in the coming decade.
Original language | English (US) |
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Pages (from-to) | 135-138 |
Number of pages | 4 |
Journal | Aging cell |
Volume | 6 |
Issue number | 2 |
DOIs | |
State | Published - Apr 2007 |
Keywords
- Antioxidants
- Caloric restriction
- Fish longevity
- Growth hormone
- Immune function
- Naked mole-rat
- Resveratrol
ASJC Scopus subject areas
- Aging
- Cell Biology