Variation in sialic acid concentration in gingival tissue from rats receiving excess vitamin A

Yvonne A.S. de Paiva, José Nicolau

Research output: Contribution to journalArticlepeer-review

Abstract

The effect of 1 to 5 doses of 15,000 I.U. of vitamin A on N‐acetyl neuraminic acid (NANA) concentration in gingival tissue from rats was studied. Increased sialic acid concentration was observed in those animals receiving up to 4 doses of the vitamin, while a decreased concentration was found in the 5 doses group. Also examined was the interrelationship between vitamin A‐cortisol and vitamin A‐ascorbic acid. The profile of NANA variation in the groups receiving vitamin A plus ascorbic acid was similar to that of animals receiving only ascorbic acid. The data obtained for the groups receiving both vitamin A and cortisol, did not differ from that obtained for the groups receiving only vitamin A.

Original languageEnglish (US)
Pages (from-to)191-195
Number of pages5
JournalJournal of Periodontal Research
Volume17
Issue number2
DOIs
StatePublished - Apr 1982
Externally publishedYes

ASJC Scopus subject areas

  • Periodontics

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