Abstract
An experiment was conducted to obtain the intrinsic material properties of the individual cell as a function of the type of substrate matrix and to investigate fundamental aspects of the response mechanism of individual cells to alterations in their biophysical environment. Using the cytointender, the effects of the three substrates (glass, Matrigel, and poly-D-lysine) were examined on the mechanical properties of 23 MG63 cells (human osteosarcoma). Cells grown on glass coated with poly-D-lysine showed significant increase in all the intrinsic indices of stiffness and the structural stiffness, when compared to the other two substrates. Its Poisson's ratio was also the smallest. In contrast, MG63 cells grown on glass were the softest.
| Original language | English (US) |
|---|---|
| Number of pages | 1 |
| State | Published - 1998 |
| Event | Proceedings of the 1998 17th Southern Biomedical Engineering Conference - San Antonio, TX, USA Duration: Feb 6 1998 → Feb 8 1998 |
Other
| Other | Proceedings of the 1998 17th Southern Biomedical Engineering Conference |
|---|---|
| City | San Antonio, TX, USA |
| Period | 2/6/98 → 2/8/98 |
ASJC Scopus subject areas
- Engineering(all)