Validation of the Diesse Mini-Ves erythrocyte sedimentation rate (ESR) analyzer using the Westergren ESR method in patients with systemic inflammatory conditions

Marc R. Happe, Daniel F. Battafarano, David P. Dooley, Thomas A. Rennie, Frederick T. Murphy, Thomas J. Casey, John A. Ward

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

The Diesse Mini-Ves (DMV) erythrocyte sedimentation rate (ESR) analyzer was designed to improve efficiency in determining the ESR. We compared the Westergren ESR method with the 4-sample DMV ESR analyzer for performance and clinical correlation. This prospective observational study, conducted at a 450-bed tertiary medical center, evaluated 291 paired samples from subjects with various systemic inflammatory conditions. Linear regression analysis revealed a statistically significant correlation between the 2 methods. Satisfactory precision of the DMV analyzer was obtained for high and mid-range ESR values. The 4-sample DMV ESR analyzer was precise and comparable in results to the Westergren ESR method. This DMV ESR analyzer is now used at our medical center based on quality control improvements that include a faster, safer, and more standardized ESR method. Hospital or office-based clinical laboratories should consider using the 4-sample DMV ESR analyzer in place of the Westergren method.

Original languageEnglish (US)
Pages (from-to)14-17
Number of pages4
JournalAmerican journal of clinical pathology
Volume118
Issue number1
DOIs
StatePublished - Jul 17 2002
Externally publishedYes

Keywords

  • Diesse Mini-Ves ESR analyzer
  • ESR
  • Erythrocyte sedimentation rate

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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