TY - JOUR
T1 - Validation of the Brazilian version of guy's neurological disability scale
AU - Araujo, Carolina Reis
AU - Simão, Luciano M.
AU - Ybarra, Mariana I.
AU - Faria, Natasha V.M.G.
AU - Botelho, Caroline M.
AU - Moreira, Marcos A.
AU - Teixeira, Antônio L.
AU - Lana-Peixoto, Marco A.
PY - 2007/9
Y1 - 2007/9
N2 - The Guy's neurological disability scale (GNDS) has recently been introduced as a new measure of disability in multiple sclerosis. It is patient-oriented, multidimensional, and not biased towards any particular disability. The purpose of the present study was to validate the Brazilian version of the GNDS. The adaptation of the scale was based on the translation/back-translation methodology. Sixty-two patients with clinically definite multiple sclerosis (CDMS) according to Poser's criteria were recruited for this study. GNDS was administered individually to each subject. The EDSS and the ambulation index (AI) scores were assigned by a neurologist. The intraclass correlation coefficient and the Cronbach's a values of the Brazilian version of GNDS (0.94 and 0.83, respectively) were comparable to the original one (0.98 and 0.79, respectively). Furthermore, the factor analysis of the Brazilian version of GNDS suggested, as the original article, a four-factor solution which accounted for 68.8% of the total variance. The Brazilian version of GNDS was found to be clinically relevant as it correlated significantly with the EDSS and AI. In conclusion, the Brazilian version of GNDS can be considered an important tool to evaluate the disability in MS patients, with clinical usefulness and psychometrics soundness.
AB - The Guy's neurological disability scale (GNDS) has recently been introduced as a new measure of disability in multiple sclerosis. It is patient-oriented, multidimensional, and not biased towards any particular disability. The purpose of the present study was to validate the Brazilian version of the GNDS. The adaptation of the scale was based on the translation/back-translation methodology. Sixty-two patients with clinically definite multiple sclerosis (CDMS) according to Poser's criteria were recruited for this study. GNDS was administered individually to each subject. The EDSS and the ambulation index (AI) scores were assigned by a neurologist. The intraclass correlation coefficient and the Cronbach's a values of the Brazilian version of GNDS (0.94 and 0.83, respectively) were comparable to the original one (0.98 and 0.79, respectively). Furthermore, the factor analysis of the Brazilian version of GNDS suggested, as the original article, a four-factor solution which accounted for 68.8% of the total variance. The Brazilian version of GNDS was found to be clinically relevant as it correlated significantly with the EDSS and AI. In conclusion, the Brazilian version of GNDS can be considered an important tool to evaluate the disability in MS patients, with clinical usefulness and psychometrics soundness.
KW - Disability
KW - Expanded disability status scale (EDSS)
KW - Guy's neurological disability scale
KW - Multiple sclerosis
UR - http://www.scopus.com/inward/record.url?scp=34548833293&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34548833293&partnerID=8YFLogxK
U2 - 10.1590/s0004-282x2007000400013
DO - 10.1590/s0004-282x2007000400013
M3 - Article
C2 - 17876401
AN - SCOPUS:34548833293
SN - 0004-282X
VL - 65
SP - 615
EP - 618
JO - Arquivos de neuro-psiquiatria
JF - Arquivos de neuro-psiquiatria
IS - 3 A
ER -