Validation of the Brazilian version of guy's neurological disability scale

Carolina Reis Araujo, Luciano M. Simão, Mariana I. Ybarra, Natasha V.M.G. Faria, Caroline M. Botelho, Marcos A. Moreira, Antônio L. Teixeira, Marco A. Lana-Peixoto

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


The Guy's neurological disability scale (GNDS) has recently been introduced as a new measure of disability in multiple sclerosis. It is patient-oriented, multidimensional, and not biased towards any particular disability. The purpose of the present study was to validate the Brazilian version of the GNDS. The adaptation of the scale was based on the translation/back-translation methodology. Sixty-two patients with clinically definite multiple sclerosis (CDMS) according to Poser's criteria were recruited for this study. GNDS was administered individually to each subject. The EDSS and the ambulation index (AI) scores were assigned by a neurologist. The intraclass correlation coefficient and the Cronbach's a values of the Brazilian version of GNDS (0.94 and 0.83, respectively) were comparable to the original one (0.98 and 0.79, respectively). Furthermore, the factor analysis of the Brazilian version of GNDS suggested, as the original article, a four-factor solution which accounted for 68.8% of the total variance. The Brazilian version of GNDS was found to be clinically relevant as it correlated significantly with the EDSS and AI. In conclusion, the Brazilian version of GNDS can be considered an important tool to evaluate the disability in MS patients, with clinical usefulness and psychometrics soundness.

Original languageEnglish (US)
Pages (from-to)615-618
Number of pages4
JournalArquivos de neuro-psiquiatria
Issue number3 A
StatePublished - Sep 2007
Externally publishedYes


  • Disability
  • Expanded disability status scale (EDSS)
  • Guy's neurological disability scale
  • Multiple sclerosis

ASJC Scopus subject areas

  • Clinical Neurology
  • Biological Psychiatry


Dive into the research topics of 'Validation of the Brazilian version of guy's neurological disability scale'. Together they form a unique fingerprint.

Cite this