Uterine activity following intravenous administration of oxytocin to the foetal Sheep

P. W. Nathanielsz, R. S. Comline, Marian Silver

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

CONCENTRATIONS of oxytocin in umbilical cord blood are high in the newborn human1 and in several species the foetal pituitary contains large amounts of oxytocin and neural lobe hormone carrier proteins, the neurophysins2,3. If the foetal posterior pituitary is to play a part in labour, however, it must not only secrete oxytocin but this oxytocin must pass from the foetal vasculature to the myometrial cell. No observations have been reported regarding the ability of oxytocin to produce uterine contractions when administered from the foetal side of the placenta.

Original languageEnglish (US)
Pages (from-to)471-472
Number of pages2
JournalNature
Volume243
Issue number5408
DOIs
StatePublished - Dec 1 1973
Externally publishedYes

ASJC Scopus subject areas

  • General

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