Uterine activity following intravenous administration of oxytocin to the foetal Sheep

P. W. Nathanielsz; R. S. Comline; Marian Silver

doi:10.1038/243471a0

Uterine activity following intravenous administration of oxytocin to the foetal Sheep

P. W. Nathanielsz, R. S. Comline, Marian Silver

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Abstract

CONCENTRATIONS of oxytocin in umbilical cord blood are high in the newborn human¹ and in several species the foetal pituitary contains large amounts of oxytocin and neural lobe hormone carrier proteins, the neurophysins^2,3. If the foetal posterior pituitary is to play a part in labour, however, it must not only secrete oxytocin but this oxytocin must pass from the foetal vasculature to the myometrial cell. No observations have been reported regarding the ability of oxytocin to produce uterine contractions when administered from the foetal side of the placenta.

Original language	English (US)
Pages (from-to)	471-472
Number of pages	2
Journal	Nature
Volume	243
Issue number	5408
DOIs	https://doi.org/10.1038/243471a0
State	Published - Dec 1 1973
Externally published	Yes

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title = "Uterine activity following intravenous administration of oxytocin to the foetal Sheep",

abstract = "CONCENTRATIONS of oxytocin in umbilical cord blood are high in the newborn human1 and in several species the foetal pituitary contains large amounts of oxytocin and neural lobe hormone carrier proteins, the neurophysins2,3. If the foetal posterior pituitary is to play a part in labour, however, it must not only secrete oxytocin but this oxytocin must pass from the foetal vasculature to the myometrial cell. No observations have been reported regarding the ability of oxytocin to produce uterine contractions when administered from the foetal side of the placenta.",

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year = "1973",

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AU - Silver, Marian

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N2 - CONCENTRATIONS of oxytocin in umbilical cord blood are high in the newborn human1 and in several species the foetal pituitary contains large amounts of oxytocin and neural lobe hormone carrier proteins, the neurophysins2,3. If the foetal posterior pituitary is to play a part in labour, however, it must not only secrete oxytocin but this oxytocin must pass from the foetal vasculature to the myometrial cell. No observations have been reported regarding the ability of oxytocin to produce uterine contractions when administered from the foetal side of the placenta.

AB - CONCENTRATIONS of oxytocin in umbilical cord blood are high in the newborn human1 and in several species the foetal pituitary contains large amounts of oxytocin and neural lobe hormone carrier proteins, the neurophysins2,3. If the foetal posterior pituitary is to play a part in labour, however, it must not only secrete oxytocin but this oxytocin must pass from the foetal vasculature to the myometrial cell. No observations have been reported regarding the ability of oxytocin to produce uterine contractions when administered from the foetal side of the placenta.

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Uterine activity following intravenous administration of oxytocin to the foetal Sheep

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