Use of the Novel Therapeutic Agent Miltefosine for the Treatment of Primary Amebic Meningoencephalitis: Report of 1 Fatal and 1 Surviving Case

Jennifer R. Cope; Dennis A. Conrad; Naiomi Cohen; Manuel Cotilla; Alexandre Dasilva; Jonathan Jackson; Govinda S. Visvesvara

doi:10.1093/cid/civ1021

Use of the Novel Therapeutic Agent Miltefosine for the Treatment of Primary Amebic Meningoencephalitis: Report of 1 Fatal and 1 Surviving Case

Jennifer R. Cope, Dennis A. Conrad, Naiomi Cohen, Manuel Cotilla, Alexandre Dasilva, Jonathan Jackson, Govinda S. Visvesvara

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

Primary amebic meningoencephalitis (PAM) is a fulminant central nervous system infection caused by the thermophilic free-living ameba Naegleria fowleri. Few survivals have been documented and adequate treatment is lacking. We report 2 PAM cases, 1 fatal and 1 surviving, treated with the novel antiparasitic agent miltefosine.

Original language	English (US)
Pages (from-to)	774-776
Number of pages	3
Journal	Clinical Infectious Diseases
Volume	62
Issue number	6
DOIs	https://doi.org/10.1093/cid/civ1021
State	Published - Jul 10 2015
Externally published	Yes

Keywords

Miltefosine
Naegleria fowleri
Primary amebic meningoencephalitis

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1093/cid/civ1021

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Use of the Novel Therapeutic Agent Miltefosine for the Treatment of Primary Amebic Meningoencephalitis : Report of 1 Fatal and 1 Surviving Case. / Cope, Jennifer R.; Conrad, Dennis A.; Cohen, Naiomi; Cotilla, Manuel; Dasilva, Alexandre; Jackson, Jonathan; Visvesvara, Govinda S.

In: Clinical Infectious Diseases, Vol. 62, No. 6, 10.07.2015, p. 774-776.

Research output: Contribution to journal › Article › peer-review

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abstract = "Primary amebic meningoencephalitis (PAM) is a fulminant central nervous system infection caused by the thermophilic free-living ameba Naegleria fowleri. Few survivals have been documented and adequate treatment is lacking. We report 2 PAM cases, 1 fatal and 1 surviving, treated with the novel antiparasitic agent miltefosine.",

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Use of the Novel Therapeutic Agent Miltefosine for the Treatment of Primary Amebic Meningoencephalitis: Report of 1 Fatal and 1 Surviving Case

Abstract

Keywords

ASJC Scopus subject areas

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