Abstract
Sibling risk ratios are used to quantify the genetic effect of two simulated disease loci, identified through TDT and association methods and characterized via components of variance derived from a relative penetrance matrix. Inconsistencies between the data set and the simulating model are also discussed. ©1995 Wiley‐Liss, Inc.
Original language | English (US) |
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Pages (from-to) | 565-570 |
Number of pages | 6 |
Journal | Genetic epidemiology |
Volume | 12 |
Issue number | 6 |
DOIs | |
State | Published - 1995 |
Keywords
- TDT
- affected sibling‐pairs
- association
- components of variance
- sibling risk ratio
- simulation
ASJC Scopus subject areas
- Epidemiology
- Genetics(clinical)