Abstract
The possibility of diagnosing oral hairy leukoplakia by means of exfoliative cytology and the Papanicolaou stain was investigated. Exfoliative cytology and punch biopsy specimens were obtained from 10 lesions that demonstrated clinical features of hairy leukoplakia. All biopsy specimens demonstrated the characteristic histopathologic features of hairy leukoplakia whereas all Papanicolaou-stained cytologic smears demonstrated condensation and margination of the nuclear chromatin (nuclear beading). All biopsy specimens and cytologic smears displayed positive Epstein-Barr virus deoxyribonucleic acid in situ hybridization. We conclude that routine exfoliative cytology may be a reliable, noninvasive, and inexpensive technique for the diagnosis of hairy leukoplakia.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 704-710 |
| Number of pages | 7 |
| Journal | Oral Surgery, Oral Medicine, Oral Pathology |
| Volume | 76 |
| Issue number | 6 |
| DOIs | |
| State | Published - 1993 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Dentistry(all)
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Use of exfoliative cytology in the diagnosis of oral hairy leukoplakia. / Migliorati, Cesar A.; Jones, Anne C; Baughman, Patricia A.
In: Oral Surgery, Oral Medicine, Oral Pathology, Vol. 76, No. 6, 1993, p. 704-710.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Use of exfoliative cytology in the diagnosis of oral hairy leukoplakia
AU - Migliorati, Cesar A.
AU - Jones, Anne C
AU - Baughman, Patricia A.
PY - 1993
Y1 - 1993
N2 - The possibility of diagnosing oral hairy leukoplakia by means of exfoliative cytology and the Papanicolaou stain was investigated. Exfoliative cytology and punch biopsy specimens were obtained from 10 lesions that demonstrated clinical features of hairy leukoplakia. All biopsy specimens demonstrated the characteristic histopathologic features of hairy leukoplakia whereas all Papanicolaou-stained cytologic smears demonstrated condensation and margination of the nuclear chromatin (nuclear beading). All biopsy specimens and cytologic smears displayed positive Epstein-Barr virus deoxyribonucleic acid in situ hybridization. We conclude that routine exfoliative cytology may be a reliable, noninvasive, and inexpensive technique for the diagnosis of hairy leukoplakia.
AB - The possibility of diagnosing oral hairy leukoplakia by means of exfoliative cytology and the Papanicolaou stain was investigated. Exfoliative cytology and punch biopsy specimens were obtained from 10 lesions that demonstrated clinical features of hairy leukoplakia. All biopsy specimens demonstrated the characteristic histopathologic features of hairy leukoplakia whereas all Papanicolaou-stained cytologic smears demonstrated condensation and margination of the nuclear chromatin (nuclear beading). All biopsy specimens and cytologic smears displayed positive Epstein-Barr virus deoxyribonucleic acid in situ hybridization. We conclude that routine exfoliative cytology may be a reliable, noninvasive, and inexpensive technique for the diagnosis of hairy leukoplakia.
UR - http://www.scopus.com/inward/record.url?scp=0027755875&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027755875&partnerID=8YFLogxK
U2 - 10.1016/0030-4220(93)90038-6
DO - 10.1016/0030-4220(93)90038-6
M3 - Article
C2 - 7506822
AN - SCOPUS:0027755875
VL - 76
SP - 704
EP - 710
JO - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
JF - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
SN - 2212-4403
IS - 6
ER -