Two DNA probes isolated from the region 5′ to the HLA-B gene are described. One of these, pCH6, detects a TaqI polymorphism which is correlated with serological alleles of HLA-B. Both probes are used to show a high level of DNA sequence homology between the 5′ flanking region of HLA-B and HLA-C.
ASJC Scopus subject areas
- Immunology and Allergy